Research Scientist

Contact: Marc Miller
Phone: 215-830-9211 x109

Job Responsibilities:

We are seeking a highly motivated scientist to join our Medicinal Chemistry research team. Working on one of our interdisciplinary drug discovery programs you will analyze SAR, propose target molecules, evaluate different routes, and synthesize molecules for biological assays. The successful candidate will work closely with scientists from our Molecular and Cellular Biology, Pharmacology and DMPK groups to efficiently evaluate and progress lead compounds. We offer a stimulating, challenging and productive discovery environment and a strong commitment to developing the Medicinal Chemistry skills of our people.

The successful candidate will:

  • Leverage scientific literature to address Medicinal Chemistry challenges and generate new ideas
  • Lead collaboratively within a dynamic team environment to achieve project goals
  • Design, synthesize and purify novel drug-like compounds
  • Organize and prioritize workload to meet timelines
  • Analyze biological data and propose new targets for synthesis
  • Communicate results, ideas and proposed plans informally and in meetings
  • Demonstrate intellectual curiosity and scientific versatility

Job Requirements:

  • Ph.D. in synthetic organic chemistry with 2-5 years of drug discovery experience
  • Significant practical experience in the successful discovery of novel kinase clinical candidates
  • Demonstrated expertise in multi-step synthesis and compound purification
  • Knowledge of common spectroscopic and analytical techniques (NMR, MS, HPLC)
  • Detail oriented and fast paced independent problem solver
  • Excellent organizational, written and oral communication skills
  • Good interpersonal skills, flexibility and the ability to lead within a team environment


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